Pharmacological studies on experimental dental caries in rats. 13. Effects of vitamin B2, B6 and anti-vitamin B6 agents on the cariogenicity and weight.

It is well known that among vitamin B agents those of B1 and B6 possess an inhibitory action of experimentally induced caries in animals but nothing definiteseems still unknown about the actions of B2 and anti-vitamin B6 agents. The present report is concerned with flavin adenine dinucleotide (to be abbreviated as F. A. D.) as B2, pyridoxine, 2-methy1-3-hydroxy-4-formy1-5-hydroxymethylpyridine-5phosphate (H. M. P.) and 4-methyl-2-aminopyridine (M. A.) as Bs, and 2-methy1-4amino-5-oxymethylpyridine (O. M. P.) as anti-vitamin B6 agents in order to ascertain their pharmacological effects on the cariogenicity on the part of experimental rats under the uniform conditions.